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Drastic Calorie Restriction for the Treatment of Massive Obesity

Nearly more than one hundred men and women with massive obesity have been admitted to our clinical unit for the administration of a 6-8 week extremely low calorie diet (300 kcal). Treatment was well tolerated, and led to a weight loss of about 20 kg body weight in men and 15 kg in women. Cardiac, respiratory and orthopedic complications of severe obesity were gradually attenuated with a progressive decrease in the need for hypoglycemic, antihypertensive, analgesic and diuretic drug administrations. This treatment proved to be particularly useful in preparation to bariatric surgery and for improving complications of severe obesity.


Mancini M, Longo K, Esposito I and Pauciullo P

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