Many studies show that the odds of maintaining weight loss after a diet or medication use are low. Even after bariatric surgery, it’s common to observe weight regain after a few years. Many factors are involved in weight regain, such as: increased hunger and decreased satiety, increased ghrelin, metabolic adaptations in thyroid axis and cortisol secretion. However, I would like to discuss mental aspects of weight regain. Modern western society is food centred. Celebrations, parties, holidays are all based on food and drink. Obese patients are always on a diet, and the doctors stimulate them to try to keep this way as long as they can stand it.